In the opening round of the 2026-27 Premier League season, Manchester United suffered a 2-0 away defeat to newly promoted Hull City, losing to the club in the top flight for the first time in their history.

Manchester United and Hull City have met 10 times in the top flight, all during the Premier League era, with United dominating the fixture with eight wins and two draws.

Hull City's last win over Manchester United came in the second leg of the 2016-17 League Cup semifinals, when Hull City beat Manchester United 2-1 but were eliminated 3-2 on aggregate.

Hull City’s last, and so far only, league victory over Manchester United came in the 1974–75 season, although it was in the second tier at the time. Hull City defeated Manchester United 2–0 on 23 November 1974, 52 years ago.

For the away team, this defeat also marks the first time in the Premier League era that they have endured a losing start in two consecutive seasons.

In the opening round of the 2025-26 Premier League season, Manchester United lost 0-1 to Arsenal at home.

In their away match against a newly promoted side in the opening round of the new Premier League season, Manchester United trailed 0-2 at halftime and ultimately lost to their opponents by the same score.

Their last consecutive league seasons with opening-match defeats date back to 1972–73 and 1973–74, when they were ultimately relegated.